Members of the PPARγ coactivator-1 (PGC-1) family of transcriptional coactivators serve as
inducible coregulators of nuclear receptors in the control of cellular energy metabolic …

Cushing's disease requires accurate diagnosis, careful treatment selection, and long-term
management to optimise patient outcomes. The Pituitary Society convened a consensus …

We are witnessing a period of renewed interest in the biology of the mitochondrion. The
mitochondrion serves a critical function in the maintenance of cellular energy stores, …

Zebrafish have become a popular organism for the study of vertebrate gene function 1 , 2 .
The virtually transparent embryos of this species, and the ability to accelerate genetic studies …

Determining the effect of gene deletion is a fundamental approach to understanding gene
function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype …

The importance of intellectual talent to achievement in all professional domains is well
established, but less is known about other individual differences that predict success. The authors …

… Because the 0.85 m aperture makes Spitzer ‘‘resolution challenged,’’ all bands sample the
point-spread function critically (0.4 k/D at 24 and 160 m, 0.3 k/D at 70 m). Thus, the instrument …

… (C) CLIP print speed contours as functions of h A and Φ 0 α PI /D c0 . (D) Photographs of
resolution test patterns using resins with different h A from (B). Colored triangles correspond to …

Objective: Recognizing the prodrome of a first psychotic episode prospectively creates the
opportunity of intervention, which could delay, ameliorate or even prevent onset. Valid criteria …

We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution,
prospective, double-blind, randomized, placebo-controlled trial within 96 hours of their …