Background Total serum IgE (tIgE) is an important intermediate phenotype of allergic
disease. Whole genome genetic association studies across ancestries may identify important …

Background While numerous genetic loci associated with atopic dermatitis (AD) have been
discovered, to date, work leveraging the combined burden of AD risk variants across the …

In aggregate, investors succumb to human temptation to buy high and sell low. Academic
research on pre-commitment provides a framework for investors to support contrarian behavior …

… Richers BS b , Patricia Taylor NP b , Lisa Beck MD c , Miguel Villarreal MS d , Keli Johnson
d , Gloria David PhD d , Mark K. Slifka PhD e , Jon Hanifin MD f , Donald YM Leung MD, PhD …

Background Atopic dermatitis (AD) is a common inflammatory skin disease with a global
prevalence ranging from 3% to 20%. Patients with AD have an increased risk for complications …

Private fond fee structures typically contain a catch-up—a widespread limited partner
preference—despite the fact that it increases fond fees and misaligns incentives. By estimating …

CD40 ligand (CD40L) is an essential effector cytokine for macrophage activation, dendritic
cell licensing, and T-cell–dependent antibody responses. Although CD40L is known to be …

After three students studied abroad to Guatemala in 2007 and witnessed firsthand the
importance of fair trade coffee to a healthy economy, they set out to make a 22-minute …

NF-κB–inducing kinase [(NIK), MAP3K14] is an essential kinase linking a subset of TNFR
family members to the noncanonical NF-κB pathway. To assess the cell-intrinsic role of NIK in …

CD40L is essential for the development of adaptive immune responses. It is generally thought
that CD40L expression in CD4 + T cells is regulated transcriptionally and made from new …