Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination
…, NG Novak, R Ingersoll, HW Sheppard… - Journal of …, 1999 - Am Soc Microbiol
The development of an effective human immunodeficiency virus type 1 (HIV-1) vaccine is
likely to depend on knowledge of circulating variants of genes other than the commonly …
likely to depend on knowledge of circulating variants of genes other than the commonly …
HIV-1 infection in individuals with the CCR5-Δ32/Δ32 genotype: acquisition of syncytium-inducing virus at seroconversion
HW Sheppard, C Celum, NL Michael… - JAIDS Journal of …, 2002 - journals.lww.com
: Homozygosity for the 32 base-pair deletion ([DELTA] 32/[DELTA] 32) in the CCR5 coreceptor
gene is associated with incomplete HIV-1 resistance. Six HIV-1-infected [DELTA] 32/[…
gene is associated with incomplete HIV-1 resistance. Six HIV-1-infected [DELTA] 32/[…
The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression
…, JR Mascola, D Dondero, DL Birx, HW Sheppard - Nature medicine, 1997 - nature.com
Cellular entry of human immunodeficiency virus type 1 (HIV-1) requires binding to both CD4
(ref. 1, 2) and to one of the chemokine receptors recently discovered to act as coreceptors 3–…
(ref. 1, 2) and to one of the chemokine receptors recently discovered to act as coreceptors 3–…
Effects of CCR5-Δ 32, CCR2-64I, and SDF-1 3′A Alleles on HIV-1 Disease Progression: An International Meta-Analysis of Individual-Patient Data
…, H Schuitemaker, HW Sheppard… - Annals of internal …, 2001 - acpjournals.org
Background: Studies relating certain chemokine and chemokine receptor gene alleles with
the outcome of HIV-1 infection have yielded inconsistent results. Objective: To examine …
the outcome of HIV-1 infection have yielded inconsistent results. Objective: To examine …
[HTML][HTML] Unintended CRISPR-Cas9 editing outcomes: A review of the detection and prevalence of structural variants generated by gene-editing in human cells
JMT Hunt, CA Samson, A Rand, HM Sheppard - Human Genetics, 2023 - Springer
Genome editing using the clustered regularly interspaced short palindromic repeats (CRISPR)
and CRISPR-associated protein (Cas) gene-editing system (CRISPR-Cas) is a valuable …
and CRISPR-associated protein (Cas) gene-editing system (CRISPR-Cas) is a valuable …
The characterization of non-progressors: long-term HIV-1 infection with stable CD4+ T-cell levels
HW Sheppard, W Lang, MS Ascher, E Vittinghoff… - Aids, 1993 - journals.lww.com
… Dr Sheppard was supported through the auspices of the Public Health Foundation of Los …
Decile 10 (II) consists of the 29 individuals with the least CD4+ cell loss; deciles 5 and 6 (H) are …
Decile 10 (II) consists of the 29 individuals with the least CD4+ cell loss; deciles 5 and 6 (H) are …
Unified rhombic lip origins of group 3 and group 4 medulloblastoma
…, J Hadley, J Golser, K Mankad, H Sheppard… - Nature, 2022 - nature.com
Medulloblastoma, a malignant childhood cerebellar tumour, segregates molecularly into
biologically distinct subgroups, suggesting that a personalized approach to therapy would be …
biologically distinct subgroups, suggesting that a personalized approach to therapy would be …
The role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression
…, KA Schultz, DE Dayhoff, CE Wang, HW Sheppard - Nature medicine, 1997 - nature.com
Entry of human immunodeficiency virus type 1 (HIV-1) into target cells requires both CD4 (ref.
1, 2) and one of a growing number of C-protein-coupled seven-transmembrane receptors …
1, 2) and one of a growing number of C-protein-coupled seven-transmembrane receptors …
Implementation lessons from the transition to telehealth during COVID-19: a survey of clinicians and young people from youth mental health services
…, A Thompson, L Valentine, P Simsir, H Sheppard… - Psychiatry …, 2021 - Elsevier
Whilst telehealth may overcome some traditional barriers to care, successful implementation
into service settings is scarce, particularly within youth mental health care. This study aimed …
into service settings is scarce, particularly within youth mental health care. This study aimed …
Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays
EL Delwart, HW Sheppard, BD Walker… - Journal of …, 1994 - Am Soc Microbiol
High mutation rates and strong selective pressures imposed on human immunodeficiency
viruses in vivo result in the formation of pools of genetic variants known as quasispecies. DNA …
viruses in vivo result in the formation of pools of genetic variants known as quasispecies. DNA …