A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates
that cause cellular toxicity and contribute to cellular proteostatic collapse. Therapeutic …

Ion channels represent highly attractive targets for drug discovery and are implicated in a
diverse range of disorders, in particular in the central nervous and cardiovascular systems. …

Most natural materials are composites based on biopolymers and some minerals. Despite
the relative paucity of these constituents, their combination yields materials with outstanding …

Severe deafness or hearing impairment is the most prevalent inherited sensory disorder,
affecting about I in 1,000 children 1 . Most deafness results from peripheral auditory defects that …

For a number of years scholars associated with the Inter-University Study of the Labour
Problems in Economic Development'have been investigating the relationships between …

The apparel and textile industries have always been at the mercy of rapidly changing styles
and fickle customers who want the latest designs while they are still in fashion. The result for …

ONE of the most direct methods of constraining the epoch at which the first galaxies formed—and
thereby to constrain the age of the Universe—is to identify and date the oldest galaxies …

The high purpose of these sessions is symbolized by a passage from Michael Polanyi: Science
is not conducted by isolated efforts like those of the chess players or shellers of peas and …

This is the first work to set one of the great bloodless revolutions of the twentieth century in its
proper historical context. John Dunlop pays particular attention to Yeltsin's role in opposing …

THE purpose of this article is twofold: it proposes first to examine qualitatively and statistically
several of the notions that have recently been set forth as descriptive of the movement of …