User profiles for Jay Lucas

James Lucas

- Verified email at cs.toronto.edu - Cited by 1766

Julian K. Lucas

- Verified email at ucsc.edu - Cited by 1347

Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

…, H Bolouri, B Montgomery, T White, JM Lucas… - Nature medicine, 2016 - nature.com
Tumor heterogeneity may reduce the efficacy of molecularly guided systemic therapy for
cancers that have metastasized. To determine whether the genomic alterations in a single …

[PDF][PDF] Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans

…, M Chen, J Varkey, T Veldman, AO Hero, J Lucas… - Cell host & …, 2009 - cell.com
Acute respiratory infections (ARIs) are a common reason for seeking medical attention, and
the threat of pandemic influenza will likely add to these numbers. Using human viral …

[HTML][HTML] Semi-automated assembly of high-quality diploid human reference genomes

…, S Koren, J Korlach, J Lee, D Li, T Lindsay, J Lucas… - Nature, 2022 - nature.com
The current human reference genome, GRCh38, represents over 20 years of effort to generate
a high-quality assembly, which has benefitted society 1 , 2 . However, it still has many …

Att3d: Amortized text-to-3d object synthesis

…, TY Lin, MY Liu, S Fidler, J Lucas - Proceedings of the …, 2023 - openaccess.thecvf.com
Text-to-3D modelling has seen exciting progress by combining generative text-to-image models
with image-to-3D methods like Neural Radiance Fields. DreamFusion recently achieved …

Optimization of 4-phenylamino-3-quinolinecarbonitriles as potent inhibitors of Src kinase activity

…, C Etienne, J Gibbons, J Grod, J Lucas… - Journal of medicinal …, 2001 - ACS Publications
Subsequent to the discovery of 4-[(2,4-dichlorophenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile
(1a) as an inhibitor of Src kinase activity (IC 50 = 30 nM), several additional …

JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

…, L Turchi, R Blanc-Mathieu, J Lucas… - Nucleic acids …, 2022 - academic.oup.com
JASPAR ( http://jaspar.genereg.net/ ) is an open-access database containing manually
curated, non-redundant transcription factor (TF) binding profiles for TFs across six taxonomic …

Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

…, J Fuscoe, R Segraves, J Lucas… - Proceedings of the …, 1988 - National Acad Sciences
Chromosomes can be specifically stained in metaphase spreads and interphase nuclei by
in situ hybridization with entire chromosome-specific DNA libraries. Unlabeled human …

Synthesis and SAR of [1,2,4]Triazolo[1,5-a]pyrimidines, a Class of Anticancer Agents with a Unique Mechanism of Tubulin Inhibition

…, J Afragola, R Hernandez, J Lucas… - Journal of medicinal …, 2007 - ACS Publications
The synthesis and SAR of a series of triazolopyrimidines as anticancer agents are described.
Treatment of 5-chloro-6-(trifluorophenyl)-N-fluoroalkyl [1,2,4]triazolo[1,5-a]pyrimidin-7-…

Exponentially weighted moving average control schemes: properties and enhancements

JM Lucas, MS Saccucci - Technometrics, 1990 - Taylor & Francis
… , we use a set of simulated observations taken from Lucas and Crosier (1982a). The data, …
We feel that it is convenient to have tables with fixed values of j. and in-control ARL’s. Table …

[HTML][HTML] Role of tau protein in both physiological and pathological conditions

J Avila, JJ Lucas, MAR Perez… - Physiological …, 2004 - journals.physiology.org
… Pérez, JJ Lucas, and J. Avila, unpublished observations). Other tau isoforms that lack exon
2… However, the model generated by Lucas et al. (199) shows spatial learning deficits and …