Background Hyperglycemia is commonly associated with the hypermetabolic stress response.
However, persistent hyperglycemia may adversely affect wound healing and immunity. …

The first randomized, blinded, placebo-controlled human trials of recombinant basic
fibroblast growth factor (bFGF) for pressure sore treatment were performed. Three different …

Wounding, of whatever form, disrupts the local environment within tissue. Wound healing
consists of a complex, integrated sequence of events that is initiated at the time of wounding …

Recent evidence from in vitro and in vivo experiments suggests that topical antimicrobials
may be toxic to fibroblasts and keratinocytes and retard wound healing. The purpose of this …

Background Severe burn induces a systemic hypermetabolic response, which includes
increased energy expenditure, protein catabolism, and diminished immunity. We hypothesized …

Toxic effects of sodium hypochlorite on wound healing elements have been confined to a
restricted range of sodium hypochlorite concentrations. We investigated concentrations of …

There exists a quantitative relationship between bacterial contamination and clinical infection.
Because of this relationship, delayed wound closure can be performed based on the …

Silicone elastomers used to make medical implants and prostheses are generally believed
to be biologically inert. However, we have seen two patients who showed severe, apparently …

Bacterial quantification of open wounds : Plastic and Reconstructive Surgery Bacterial
quantification of open wounds : Plastic and Reconstructive Surgery AMERICAN SOCIETY OF …

Experimental ischemia by the classic frostbite rabbit ear model clearly defined the role of
thromboxane as a mediator of progressive dermal ischemia in frostbite injuries. The therapeutic …