We are a group of archaeologists, anthropologists, curators and geneticists representing
diverse global communities and 31 countries. All of us met in a virtual workshop dedicated to …

… A homotrimeric form of CD40L has also been produced by adding a mutated leucine zipper
motif to the amino terminus (M. Spriggs et ai., unpublished). Alone, the dimer has low activity …

Importance Leisure-time physical activity has been associated with lower risk of heart-disease
and all-cause mortality, but its association with risk of cancer is not well understood. …

THE CD40 surface molecule is a 277-amino-acid glycoprotein expressed on B lymphocytes,
epithelial cells and some carcinoma cell lines. Monoclonal antibodies against CD40 …

Herpesvirus Saimiri gene 13 (HVS13) exhibits 57% identity with the predicted sequence of
a T cell-derlved molecule termed CTLAI. Recombinant HVS13 and CTLA8 stimulate …

For decades cell biologists have relied on viruses to facilitate the study of complex cellular
function. More recently, the tragedy of the AIDS epidemic has focused considerable human …

A cDNA encoding human IL-17 (hIL-17) was cloned from a CD4+ T cell library. The predicted
155-amino acids sequence contains an N-terminal signal peptide and exhibits 72% amino …

The ligand for CD40 (CD40L) is a membrane glycoprotein on activated T cells that induces
B cell proliferation and immunoglobulin secretion. Abnormalities in the CD40L gene were …

CD40 is a member of the tumor necrosis factor (TNF) receptor family of cell surface proteins
and was originally described as a B cell restricted antigen. Treatment of primary human …

Two major antigenic subgroups (designated A and B) have been described for human
respiratory syncytial virus (RSV). Previously, on the basis of reactivity patterns with monoclonal …