Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
We conducted a meta-analysis of Parkinson's disease genome-wide association studies
using a common set of 7,893,274 variants across 13,708 cases and 95,282 controls. Twenty-six …
using a common set of 7,893,274 variants across 13,708 cases and 95,282 controls. Twenty-six …
Accelerating retail supply chain performance against pandemic disruption: adopting resilient strategies to mitigate the long-term effects
Purpose Coronavirus disease 2019 (COVID-19) has disrupted global supply chains, revealing
dreadful gaps and exposing vulnerabilities. Retailers are challenged to tackle risks and …
dreadful gaps and exposing vulnerabilities. Retailers are challenged to tackle risks and …
The safety, tolerability and risks associated with the use of newer generation antidepressant drugs: a critical review of the literature
Newer generation antidepressant drugs (ADs) are widely used as the first line of treatment
for major depressive disorders and are considered to be safer than tricyclic agents. In this …
for major depressive disorders and are considered to be safer than tricyclic agents. In this …
Cell biology and pathophysiology of α-synuclein
α-Synuclein is an abundant neuronal protein that is highly enriched in presynaptic nerve
terminals. Genetics and neuropathology studies link α-synuclein to Parkinson’s disease (PD) …
terminals. Genetics and neuropathology studies link α-synuclein to Parkinson’s disease (PD) …
Optimization criteria for optimal placement of piezoelectric sensors and actuators on a smart structure: a technical review
This article presents in a unified way, the various optimization criteria used by researchers
for optimal placement of piezoelectric sensors and actuators on a smart structure. The article …
for optimal placement of piezoelectric sensors and actuators on a smart structure. The article …
Developing a framework for enhancing survivability of sustainable supply chains during and post-COVID-19 pandemic
The pandemic has created a restrictive working system including remote working, and flexible
hours for the firms and employees all around the globe, thus transforming into a platform …
hours for the firms and employees all around the globe, thus transforming into a platform …
[HTML][HTML] Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease
…, T Samaddar, C Schulte, M Sharma… - … England Journal of …, 2009 - Mass Medical Soc
Background Recent studies indicate an increased frequency of mutations in the gene
encoding glucocerebrosidase (GBA), a deficiency of which causes Gaucher's disease, among …
encoding glucocerebrosidase (GBA), a deficiency of which causes Gaucher's disease, among …
Genome-wide association study reveals genetic risk underlying Parkinson's disease
We performed a genome-wide association study (GWAS) in 1,713 individuals of European
ancestry with Parkinson's disease (PD) and 3,978 controls. After replication in 3,361 cases …
ancestry with Parkinson's disease (PD) and 3,978 controls. After replication in 3,361 cases …
α-Synuclein promotes SNARE-complex assembly in vivo and in vitro
Presynaptic nerve terminals release neurotransmitters repeatedly, often at high frequency,
and in relative isolation from neuronal cell bodies. Repeated release requires cycles of …
and in relative isolation from neuronal cell bodies. Repeated release requires cycles of …
[HTML][HTML] Enhancing supply chain performance using RFID technology and decision support systems in the industry 4.0–A systematic literature review
Supply Chain processes are continuously marred by myriad factors including varying demands,
changing routes, major disruptions, and compliance issues. Therefore, supply chains …
changing routes, major disruptions, and compliance issues. Therefore, supply chains …