Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53
NH Chehab, A Malikzay, M Appel… - Genes & …, 2000 - genesdev.cshlp.org
Chk2/hcds1, the human homolog of theSaccharomyces cerevisiae RAD53/SPK1
andSchizosaccharomyces pombe cds1 DNA damage checkpoint genes, encodes a protein kinase …
andSchizosaccharomyces pombe cds1 DNA damage checkpoint genes, encodes a protein kinase …
[HTML][HTML] A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
…, JG Bixby, M Felices, L Zheng, M Appel… - Journal of Biological …, 2003 - ASBMB
Members of the tumor necrosis factor (TNF) receptor (TNFR) superfamily are potent regulators
of apoptosis, a process that is important for the maintenance of immune homeostasis. …
of apoptosis, a process that is important for the maintenance of immune homeostasis. …
Subtype-specific alterations of γ-aminobutyric acid and glutamatein patients with major depression
…, CN Epperson, YT Wu, M Appel… - Archives of general …, 2004 - jamanetwork.com
Background Measurement of cortical γ-aminobutyric acid (GABA) and glutamate concentrations
is possible using proton magnetic resonance spectroscopy. An initial report, using this …
is possible using proton magnetic resonance spectroscopy. An initial report, using this …
Studies of streptozotocin-induced insulitis and diabetes.
…, AA Like, WL Chick, MC Appel… - Proceedings of the …, 1977 - National Acad Sciences
Multiple small injections of streptozotocin produce a delayed, progressive increase in plasma
glucose in mice within 5-6 days after the injections, in association with pronounced insulitis …
glucose in mice within 5-6 days after the injections, in association with pronounced insulitis …
Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand.
…, DL Greiner, NE Phillips, MC Appel… - Proceedings of the …, 1995 - National Acad Sciences
Combined treatment with allogeneic small lymphocytes or T-depleted small lymphocytes plus
a blocking antibody to CD40 ligand (CD40L) permitted indefinite pancreatic islet allograft …
a blocking antibody to CD40 ligand (CD40L) permitted indefinite pancreatic islet allograft …
Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44
…, M Brusilovsky, U Hadad, D Oz, MY Appel… - The Journal of …, 2011 - journals.aai.org
NK cells play an important role in the early immune response to cancer. The NKp44 activating
receptor is the only natural cytotoxicity receptor that is expressed exclusively by primate …
receptor is the only natural cytotoxicity receptor that is expressed exclusively by primate …
Requirement of the JIP1 scaffold protein for stress-induced JNK activation
…, N Kelkar, TF Haydar, JP Mordes, M Appel… - Genes & …, 2001 - genesdev.cshlp.org
The c-Jun N-terminal kinase (JNK) signal transduction pathway is activated in response to
the exposure of cells to environmental stress. Components of the JNK signaling pathway …
the exposure of cells to environmental stress. Components of the JNK signaling pathway …
The effect of iodide ingestion on the development of spontaneous lymphocytic thyroiditis in the diabetes-prone BB/W rat
EM ALLEN, MC APPEL, LE BRAVERMAN - Endocrinology, 1986 - academic.oup.com
It has been suggested that the incidence of Hashimoto’s thyroiditis is increased in the presence
of high iodide intake. The diabetes-prone BB/W rat develops spontaneous histological …
of high iodide intake. The diabetes-prone BB/W rat develops spontaneous histological …
Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with CB-17-scid/scid mice
DL Greiner, LD Shultz, J Yates, MC Appel… - The American journal …, 1995 - ncbi.nlm.nih.gov
T and B lymphocyte-deficient mice homozygous for the severe combined immunodeficiency
(SCID) mutation can be immunologically engrafted with human lymphocytes. However, low …
(SCID) mutation can be immunologically engrafted with human lymphocytes. However, low …
Association with soil bacteria enhances p38-dependent infection resistance in Caenorhabditis elegans
S Montalvo-Katz, H Huang, MD Appel… - Infection and …, 2013 - Am Soc Microbiol
The importance of our inner microbial communities for proper immune responses against
invading pathogens is now well accepted, but the mechanisms underlying this protection are …
invading pathogens is now well accepted, but the mechanisms underlying this protection are …