Following damage to the ventromedial prefrontal cortex, humans develop a defect in real-life
decision-making, which contrasts with otherwise normal intellectual functions. Currently, …

… Kaplan joined Acorn’s board of directors in 2001 and began to collaborate with Anderson …
with Anderson’s time algorithms for modeling transaction complexity. Kaplan and Anderson …

The long-term consequences of early prefrontal cortex lesions occurring before 16 months
were investigated in two adults. As is the case when such damage occurs in adulthood, the …

The term “real-world evidence” is widely used by those who develop medical products or
who study, deliver, or pay for health care, but its specific meaning is elusive. We believe it …

We tested the hypothesis that cognitive functions related to working memory (assessed with
delay tasks) are distinct from those related to decision making (assessed with a gambling …

A decision-making instrument known as the ‘gambling task’ was used, which has been shown
to be sensitive to the decision-making impairment of patients with bilateral lesions of the …

We examined the sensitivity and specificity of the Wisconsin Card Sorting Test (WCST) as a
measure of frontal lobe damage in 91 subjects with stable focal brain lesions. Anatomical …

Although this is a time of unprecedented progress in cognitive neuroscience, clinicians who
evaluate and treat frontal lobe dysfunction still face many of the frustrations encountered by …

CD4 T cell activation leads to proliferation and differentiation into effector (Teff) or regulatory
(Treg) cells that mediate or control immunity. While each subset prefers distinct glycolytic or …

Epstein-Barr virus (EBV) establishes a persistent latent infection in peripheral B lymphocytes
in humans and is associated with a variety of malignancies and proliferative disorders. …