The interaction of nuclear pore proteins (Nups) with active genes can promote their transcription.
In yeast, some inducible genes interact with the nuclear pore complex both when active …

Penicillin binding proteins (PBPs) are membrane-associated proteins that catalyze the final
step of murein biosynthesis. These proteins function as either transpeptidases or …

Within the nucleus, chromatin is functionally organized into distinct nuclear compartments.
The nuclear periphery, containing Nuclear Pore Complexes (NPCs), plays an important role …

Genomes have complex three-dimensional structures. High-resolution population-based
biochemical studies over the last decade have painted a mostly static picture of the genome …

Previously expressed inducible genes can remain poised for faster reactivation for multiple
cell divisions, a conserved phenomenon called epigenetic transcriptional memory. The GAL …

In budding yeast, targeting of active genes to the nuclear pore complex (NPC) and
interchromosomal clustering is mediated by transcription factor (TF) binding sites in the gene …

On activation, the GAL genes in yeast are targeted to the nuclear periphery through interaction
with the nuclear pore complex. Here we identify two cis-acting “DNA zip codes” from the …

OBJECTIVES:: Glutathionyl haemoglobin (GS-Hb) belonging to the class of glutathionylated
proteins has been investigated as a possible marker of oxidative stress in different chronic …

The past decades have provided remarkable insights into how the eukaryotic cell nucleus
and the genome within it are organized. The combined use of imaging, biochemistry and …

Certain genes show more rapid reactivation for several generations following repression, a
conserved phenomenon called epigenetic transcriptional memory. Following previous …